This course will discuss the principles and applications of medical imaging in patient care. There will be an emphasis on radiopharmaceuticals and nuclear medicine imaging (SPECT and PET) but other imaging technologies will be discussed including MRI, ultrasound, X-ray, mammography and CT. These technologies are applied in diagnosing infectious disease, cancer, cardiovascular disease, hepatobiliary and renal dysfunction, and neurological disorders. The emerging role of molecular imaging using PET and SPECT in selecting patients for personalized medicines for cancer as well as monitoring response to these new therapies will be introduced.